First drive to Shakotan peninsula. After cape Kamui and Shimamui coast sightseeing, next destination is Otaru. Old Canal, Kitaichi Glass factory and Musical Box factory should be on the list to visit. You may see some SAKURA at Temiya park if early May. Then 1 hr drive to Jozankei onsen
Overnight in Jozankei

Stopover at Fukidashi park where you can collect spring water come from Mt. Yotei. Then drive to Lake Toya for a great view. Lake Hill farm is good for tasting a ice cream. Visit two volcanoes, Mt.Usu and Showashinzan before arriving in Noboribetsu, one of the greatest onsen town in Japan
Overnight in Noboribetsu

In Noboribetsu Hell valley, Oyunuma, Date Jidaimura etc. are tourist attractions. SAKURA street is very beautiful if you drive in May. National ainu museum called UPOPOY where you learn and enjoy Hokkaido native “AINU” is a new destination on the way back to Sapporo.